Biodiversity Genomics Lab
Welcome to Zhang's Lab

On the last page of The Origin of Species, Darwin writes that there is grandeur in the view that all of life had a single beginning from which evolved endless forms most beautiful and most wonderful. In the over 150 years that passed, biology has made tremendous progress understanding the pathways and molecular processes behind the diversification of the life forms, and evolution's fundamental genetic mechanisms that Darwin was unaware of became firmly established via the Neodarwinian synthesis in the first half of the 20th century. The second half of the 20th century added all aspects of social evolution to the Neodarwinian synthesis after W.D. Hamilton developed inclusive fitness theory in the 1960s and 1970s. In spite of these major developments we continue to know very little about the fundamental molecular processes that produce adapted phenotypes in response to variation in the physical and social environment of organisms. The next generation sequencing revolution has
demonstrated this very clearly in that we are now generating reference genomes at a higher rate that we can study how these blueprints translate in responses to natural selection, the adaptations arising from these responses, and the ultimate diversification and speciation processes that may or may not follow. We have developed and applied comparative genomic tools on high throughput '-omics' data to address the classical questions of diversification, adaptation and speciation across a broad spectrum of organisms. Our group is also interested in the evolution of eusocial insects and behaviors. We have initiated and participated in many comparative genomic studies in eusocial insects and now are focusing on the functional genomic study to understand how the genetic and epigenetic processes regulate the caste development and the behavioural plasticity in eusocial insects.
Top News

2019/01/18Using whole genome sequencing of contemporary and historic crested ibis, our group explore how their genetic diversity has changed through time. Study is now published on Current Biology!
2018/11/28Guojie Zhang was recognized as a Highly Cited Researcher for 2018 in Cross-Field by Calrivate Analytics
2018/10/24Our comparative transcriptomic study in reconstructing the ancestral brain genetic regulatory network for caste systems in ants is now published on Nature Ecology & Evolution!
2018/08/06The population study of the genetic mechanism underlying the rapid behavior changes under the domestication experiment for red fox is published in Nature ecology & evolution.
2018/04/24First AsiaEvo, Connecting Asian Evolutionary Biologists to the World! Over 800 delegates from 34 countries met in Shenzhen, China from 18-20 April for the first AsiaEvo Conference. The conference hosted 44 symposia and attracted contributions from many fields.
2018/02/19The hologenomic study of the common vampire bat genome and its gut metagenome is published in Nature ecology & evolution
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